Cambridge Healthtech Institute’s 2nd Annual 

Protein & Antibody Engineering 
蛋白质和抗体工程
Innovative Engineering * Novel Scaffolds * Bispecific Antibodies

March 31-April 1, 2015

 

The field of protein engineering is at an exciting point in its development, with new generations of protein and antibody formats entering the market, improved understanding of structure-function relationships, and creative engineering that promises to optimize molecules with improved biophysical properties.

The Protein & Antibody Engineering conference presents the state of the art in strategies and techniques to enhance antibody binding and specificity, design of novel scaffolds with increased potency, as well as new and enhanced applications for bispecific antibodies.


JOINT PLENARY KEYNOTE PRESENTATIONS

Antibody Development Strategies in Today’s China

Chengbin Wu, Ph.D., President, Research & Development and CSO, Shanghai C P Guojian Pharmaceutical Co. Ltd., PR China

ADC: Is It Time to Rethink Some Preconceptions?

Jaume Pons, Ph.D., Senior Vice President and CSO, Rinat


ENHANCING ANTIBODY BINDING AND SPECIFICITY

Antibody Engineering for Better in vivo Efficacy

Weidong Jiang, Ph.D., CSO, Henlius Biopharmaceuticals, Inc.

In vitro and in vivo Study of pH-Dependent Antigen Binding Antibody with Increased FcgammaRIIB Binding

Yuji Hori, Ph.D., Research Scientist, Chugai Pharmaceutical, Japan


NOVEL PROTEINS AND ALTERNATIVE SCAFFOLDS

Anticalins: Versatile Binding Proteins based on a Flexible Natural Scaffold

Arne Skerra, Ph.D., Professor, Technische Universität München; Founder, Pieris AG, Germany

ADAPT - A Novel Scaffold Protein for Radionuclide Molecular Imaging

Johan Nilvebrant, Ph.D., Postdoctoral Researcher, The Donnelly Centre, Center for Cellular and Biomolecular Research, University of Toronto, Canada

Exceptionally Potent and Broad Inhibitors of HIV-1 based on Antibody Domains and One Domain Soluble CD4 Multivalent Fusion Proteins

Dimiter Dimitrov, Ph.D., Senior Investigator, NCI, National Institutes of Health

Cross-Neutralizing Single-Domain Antibodies to Pandemic Influenza

Simon E Hufton, Ph.D., Principal Scientist, Biotherapeutics, National Institute for Biological Standards and Control (NIBSC)


ENGINEERING OF BISPECIFIC ANTIBODIES

Antibody Engineering Strategies for the Production of Bispecific Heterodimeric IgG in Mammalian Cells

Wei Yan, Ph.D., Director, Research, Therapeutic Discovery, Amgen, Inc.

Design and Development of Next-Generation Bispecific Antibodies with Good Drug-Like Properties (DLP)

Jinming Gu, Ph.D., Senior Scientist, Global Biologics, Abbvie, Inc.

Bispecific Antibody Formats Tailored for Specific Applications

Jochen Kruip, Ph.D., Department Head, BioInnovation Novel Therapeutic Protein Formats, Sanofi

Therapeutic Applications of DART Proteins – What’s Next?

Syd Johnson, Ph.D., Vice President, Antibody Engineering, MacroGenics, Inc.

Targeted Delivery of Nanomedicines Using Bispecific Antibodies

Stephen Mahler, Ph.D., Professor, Australian Institute for Bioengineering and Nanotechnology, University of Queensland

The Development of Antibody-Based Therapeutics for the Treatment of Emerging Infectious Diseases

Tianlei Ying, Ph.D., Head, Antibody Engineering and Drug Discovery Group, School of Basic Medical Science, Fudan University

Clinical Development of Tanibirumab and Its Bispecific Antibody, DIG-KT

Jin-San Yoo, Ph.D., President & CEO, PharmAbcine, Inc., Korea




For questions about the meeting, please contact: 

Mimi Langley 郭咪咪
Sr. Conference Director
Cambridge Healthtech Institute
Phone: +1 816-472-0701
Email: mlangley@healthtech.com 

For partnering & sponsorship information, please contact: 

Companies A-K 

Jason Gerardi
Manager, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5452
Fax: 781-972-5470
Email: jgerardi@healthtech.com 

Companies L-Z 

Carol Dinerstein
Director, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5471
Fax: 781-972-5470
Email: dinerstein@healthtech.com 


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Track 1

Protein Engineering 

Track 2

Phage & Yeast Display 

Track 3

Antibody-Drug Conjugates 

Track 4

Characterization of Biotherapeutics